QB, OL and then WR sounds about right for achieving a decent passing game. A decent OC wouldn't hurt as well, but as we've seen a number of times, the great QB's will find a way to be successful.
I think Ponder has a chance at being a franchise guy, but don't know if I am certain enough about it to let a Luck or RGIII go by if available.
Trading down isn't out of the question, if you can get the right picks to make it work.
I would still make the pick based on what the talent evaluators indicate is the BPA. Don't just take the best OL, WR, or CB available, take the player that has the best chance at truly being great and he will instantly upgrade those around him.