- Lions QB Daunte Culpepper was the Vikings’ first pick in the 1999 NFL Draft and the 11th player chosen overall. He started 80 games for the Vikings and ranks 2nd in team history with a 91.5 rating, and third in yards (20,162) and TD passes (135).
- Detroit’s offensive coordinator, Scott Linehan was the offensive co- ordinator and quarterback coach for the Vikings from 2002-2004.
- Lions CB Marcus McCauley was drafted by the Vikings in 2007 and played for the Vikings in 2007 and 2008, before being cut after the 2009 preseason.
- Vikings TE coach Jimmie Johnson played for the Detroit Lions from 1992-93.
- Vikings Vice President of Player Personnel Rick Spielman worked as a college scout for the Lions from 1990-94 and as a pro scout from 1995-96. His brother, Chris, played LB for the Lions from 1988-95.
- Detroit’s offensive quality control coach, Todd Downing held the same position with the Vikings in 2005. Prior to that he was a football systems analyst for the Vikings in 2003 and 2004.

- Vikings RB Chester Taylor is from River Rouge, MI.
- Vikings G Steve Hutchinson played at the University of Michigan from 1997-2000.
- Lions Head Coach Jim Schwartz was a graduate assistant at the University of Minnesota in 1990 and 1991.
- Lions QB coach Jeff Horton began his coaching career as a graduate assistant at the University of Minnesota.
- Lions Asst. Director of Pro Personnel Charlie Sanders played collegiately at the University of Minnesota.

- QB Brett Favre and Lions DE Jason Hunter and DT Grady Jackson were teammates in GB in 2006 & 2007.
- Lions S Marquano Manuel was coached in Cincinnati in 2003 by Vikings defensive coordinator Leslie Frazier, played in Seattle in 2004 and 2005 with Vikings G Steve Hutchinson, in 2006 in GB with Brett Favre, and in Denver with Vikings CB Karl Paymah in 2008.
- Hutchinson blocked for RB Maurice Morris in Seattle from 2002-2005.
- Vikings DT Pat Williams and CB Antoine Winfield were teammates of Lions running backs coach Sam Gash with the Buffalo Bills.

- Vikings G Steve Huchinson was teammates at Michigan with Lions LB Larry Foote and tackles Jeff Backus and Jon Jansen.
- Vikings 2009 3rd-round draft pick Asher Allen and Lions 1st-round draft pick (1st overall) Matthew Stafford played together at Georgia.
- Vikings DE Ray Edwards played at Purdue with Lions DE Cliff Avril.
- S Ko Simpson played at South Carolina with Vikings WR Sidney Rice
- Vikings T Bryant McKinnie played at Miami (Fla.) with Lions CB Phillip Buchanon