- Vikings DL Jared Allen was drafted by Kansas City and played for the Chiefs from 2004-07. This will be Allenís first game against his former team.
- Vikings tight ends coach Jimmie Johnson played TE for Kansas City in 1994.
- Vikings defensive coordinator Fred Pagac was the Chiefs linebackers coach from 2004-05.
- Vikings Special Teams Coordinator Mike Priefer was an assistant with Kansas City from 2006-08.
- Vikings running backs coach James Saxon played for the Chiefs from 1988- 1991 and returned as an assistant coach from 2001-07., where he coached the number 1 and 2 rushers in Chiefs history, Priest Holmes and Larry Johnson.
- Chiefs defensive backs coach Emmitt Thomas was an assistant coach for the Vikings from 2000-01.
- Chiefs quarterback coach Jim Zorn was the University of Minnesota Quarterbacks coach from 1995-96.

- Vikings WR Bernard Berrian played with Chiefs RB Thomas Jones for the Chicago Bears from 2004-06.
- Vikings T Charlie Johnson and WR Devin Aromashodu played together with Chiefs G Ryan Lilja for the Indianapolis Colts.
- Vikings G Steve Hutchinson played with Chiefs WR Jerheme Urban from 2003-05 with the Seattle Seahawks.
- Vikings WR Michael Jenkins teamed with Chiefs LB Demorrio Williams with the Atlanta Falcons from 2004-07.
- Vikings DT Fred Evans, WR Greg Camarillo and RB Lorenzo Booker played with Chiefs CB Travis Daniels together with the Miami Dolphins.
- Vikings Personnel Consultant Paul Wiggin was the Head Coach of the Chiefs from 1975-1977.

- Vikings QB Christian Ponder and DT Letroy Guion played with Chiefs C Rodney Hudson at Florida State.
- Vikings CB Asher Allen and Chiefs LB Justin Houston played together at Georgia.
- Vikings LB Erin Henderson and Chiefs OT Jared Gaither were college teammates at Maryland.
- Vikings S Jamarca Sanford played with Chiefs DB Kendrick Lewis, WR Dexter McCluster, and NT Jerrell Powe at Mississippi.
- Vikings WR Greg Camarillo teamed with Chiefs DE Amon Gordon at Stanford.
- Vikings G Anthony Herrera played with Chiefs P Dustin Colquitt at Tennessee.
- Vikings DB Cedric Griffin, DE Brian Robison, and LS Cullen Loeffler attended Texas with Chiefs LB Derrick Johnson.
- Vikings CB Chris Cook played with Chiefs T Branden Albert at Virginia.
- Vikings LB Xavier Adibi and Chiefs CB Brandon Flowers teamed together at
Virginia Tech.