Well the only team with a shot at Clowney and Nix both is the Rams if they get two top ten selections.
People may not be the biggest fans of it, but I'm warming up more and more to the thought of Manziel. He has a lot of stuff to work on, but his poise in the pocket and ability to keep his eyes downfield are top notch. Like really good. He's a bit of an improviser a la Romo, but that's kind of what we've been missing since Ponder arrived. Bridgewater is still a better prospect but the gap isn't enormous IMO.
If there isn't a QB the front office is a fan of, then on defense just take either Barr, Clowney or trade back a bit and grab Nix. Barr would probably be my favourite of that group. Less physically gifted but more of a gamer than Clowney. Either one would be a great fit.
A lot depends on who our head coach is come draft day. My favourite would probably be Mike Zimmer. I think our personnel (especially with Barr) would fit an aggressive 4-3 defense really well and he's had a good one in Cincinatti.